At least 2,300 people are known to have died, and the death toll is expected to rise as officials dig through the rubble.
Tremors were also felt in Bihar, Uttar Pradesh, Odisha, West Bengal, Assam and Jharkhand. A total of 57 people have lost their lives in India, 262 people were reportedly injured, 56 buildings fully damaged and 248 buildings partially damaged.
The quake struck an area between the capital, Kathmandu, and the city of Pokhara, the US Geological Survey said. Tremors were felt across the region, with further loss of life in India, Bangladesh and on Mount Everest.
The earthquake collapsed houses, leveled centuries-old temples and triggered avalanches in the Himalayas. It was the worst temblor to hit the poor South Asian nation in over 80 years.
The quake struck before noon time and was most severely felt in the capital as well as the densely populated Kathmandu Valley. A magnitude-6.6 aftershock hit about an hour later, and smaller aftershocks continued to ripple through the region for hours.
Please pray for everyone affected by the earthquake, for those who have lost loved ones, and for families whose homes have been destroyed. Pray that God will grant wisdom as relief agencies determine how to respond, and that the work of Christian relief agencies will convey the love of Christ.